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Am J Trop Med Hyg ; 103(5): 1983-1985, 2020 11.
Article in English | MEDLINE | ID: covidwho-771325

ABSTRACT

COVID-19 has now spread globally, and 10-20% of the cases are thought to proceed to a severe condition. However, information on COVID-19 in immunodeficient patients remains limited. We treated a 56-year-old man who developed COVID-19 after chemotherapy for mantle cell lymphoma. After 1 month of prolonged fever, the patient's respiratory condition deteriorated rapidly, and he died. COVID-19 in immunocompromised patients after chemotherapy, even with mild symptoms, can cause rapid immune reconstitution and respiratory deterioration. Therefore, caution is advised until negative PCR test results for SARS-CoV-2 are confirmed.


Subject(s)
Bone Marrow Failure Disorders/chemically induced , COVID-19/etiology , Cross Infection/chemically induced , Lymphoma, Mantle-Cell/drug therapy , SARS-CoV-2/isolation & purification , Bone Marrow Failure Disorders/complications , COVID-19/diagnostic imaging , Cross Infection/complications , Cross Infection/etiology , Humans , Immunocompromised Host , Lymphoma, Mantle-Cell/complications , Lymphoma, Mantle-Cell/immunology , Male , Middle Aged , Pharynx/virology , Polymerase Chain Reaction , Radiography, Thoracic , SARS-CoV-2/genetics , Tomography, X-Ray Computed , COVID-19 Drug Treatment
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